What medications increase the risk of osteoporosis?
Several medications and medical treatments can potentially weaken bone density. However, it’s important to note that the risk can vary depending on factors such as the type of medication, dosage, duration of treatment, and individual susceptibility.
- Corticosteroids: Long-term use of steroids like prednisone or cortisone is a significant risk factor for medication-induced osteoporosis. These medications suppress bone formation and impair calcium absorption.
- Seizure Medications: Some antiepileptic medications, including phenytoin, carbamazepine, and phenobarbital, can interfere with the metabolism of Vitamin D and calcium, leading to decreased bone density.
- Antidepressants: Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine and paroxetine, have been associated with a modest increase in fracture risk, possibly due to their impact on bone turnover.
- Proton Pump Inhibitors (PPIs): Long-term use of PPIs like omeprazole and esomeprazole, used to treat acid reflux and stomach ulcers, impair calcium absorption.
- Thyroid Hormone Replacement: Excessive thyroid hormone replacement in individuals with hypothyroidism can increase the risk of osteoporosis.
- Immunosuppressants: Some medications used to suppress the immune system, such as methotrexate and cyclosporine, may affect bone health when used long-term.
- Blood Thinners: Prolonged use of high-dose heparin and certain anticoagulants may contribute to bone loss.
- Chemotherapy: Some chemotherapy agents, particularly in high doses or when used in combination with other treatments, can have detrimental effects on bone density.
Can spinal compression fractures be related to osteoporosis?
Yes, compression fractures in the spine are a common consequence of osteoporosis. Often, people with osteoporosis do not know they have the condition until they experience a fracture.
When osteoporosis causes compression fractures in the spine, the bones of the spine become so fragile that even normal everyday activities, such as bending, lifting, or coughing, can exert damaging pressure on the vertebrae. These fractures typically occur in the front (anterior) part of the vertebral body, causing it to collapse or compress.
Compression fractures can be สมัครสมาชิก UFABET วันนี้ รับเครดิตฟรีทุกวัน painful and may cause localized back pain. Which can range from mild to severe. Some individuals may also experience nerve-related symptoms, such as numbness, tingling, or weakness, if the fractured vertebrae put pressure on nearby nerves.